发明名称 |
Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives |
摘要 |
The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hydroxybutyric acid derivatives by ketoreductase-catalyzed conversion of 4-halo-3-ketobutyric acid derivatives The present invention also provides methods and compositions for preparing vicinal cyano, hydroxyl substituted carboxylic acid esters.
|
申请公布号 |
US2007161094(A1) |
申请公布日期 |
2007.07.12 |
申请号 |
US20060502745 |
申请日期 |
2006.08.10 |
申请人 |
CODEXIS, INC. |
发明人 |
DAVIS S. C.;GRATE JOHN H.;GRAY DAVID R.;GRUBER JOHN M.;HUISMAN GJALT W.;MA STEVEN K.;NEWMAN LISA M.;SHELDON ROGER;WANG LI A. |
分类号 |
C12P13/00;A61K;C12N1/14;C12N9/14;C12P7/64 |
主分类号 |
C12P13/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|