发明名称 |
MODIFIED RELEASE FORMULATIONS OF TRAMADOL AND USES THEREOF |
摘要 |
<p>The present invention relates to specific types of controlled and modified release dosage forms containing tramadol or at least one pharmaceutically acceptable salt, enantiomer, or metabolite- thereof, that possess specific pharmacokinetic properties and which desirably are not subject to dose dumping, e.g., induced by food or alcohol. The invention also relate to methods of making and using these controlled and modified release dosage forms in therapeutic regimens wherein tramadol is therapeutically effective.</p> |
申请公布号 |
WO2007078895(A2) |
申请公布日期 |
2007.07.12 |
申请号 |
WO2006US48100 |
申请日期 |
2006.12.18 |
申请人 |
BIOVAIL LABORATORIES INTERNATIONAL S.R.L.;MAMAJIWALLA, SALIM;FRISBEE, STEVE |
发明人 |
MAMAJIWALLA, SALIM;FRISBEE, STEVE |
分类号 |
A61K9/22;A61K9/32;A61K9/42 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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