发明名称 PLATINUM COMPLEXES FOR TARGETED DRUG DELIVERY
摘要 The subject invention concerns biotin-conjugated platinum complexes that exhibit direct and indirect (immunological) antitumor cell activity. The subject invention also concerns the biotin-platinum complexes of the invention that have another molecule, such as an antibody, a ligand, a receptor, etc., bound to the biotin moiety. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the invention can also be used to treat or prevent infection by a virus or a bacterial or parasitic organism in vivo or in vitro.
申请公布号 WO2007008247(A3) 申请公布日期 2007.07.05
申请号 WO2005US41129 申请日期 2005.11.10
申请人 UNIVERSITY OF SOUTH FLORIDA;KAY, HEIDI 发明人 KAY, HEIDI
分类号 C07F15/00 主分类号 C07F15/00
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