发明名称 |
THERMOSETTING NEUTRALIZED CHITOSAN COMPOSITION FORMING A HYDROGEL, LYOPHILIZATE, AND PROCESSES FOR PRODUCING THE SAME |
摘要 |
The aqueous thermosetting neutralized chitosan composition, forming a phosphate-free transparent hydrogel at a temperature higher than 5° C., comprises 0.1 to 5.0 w/w %, based on the total composition, of a reacetylated chitosan having a molecular weight of not smaller than 100 kDa and a deacetylation degree of 40 to 70%, neutralized with an hydroxylated base, and 1 to 30 w/w %, based on the total composition, of a complexing agent selected from polyoses and polyols derived from polyoses. Said composition is useful for the preparation of an injectable formulation. |
申请公布号 |
CA2634479(A1) |
申请公布日期 |
2007.07.05 |
申请号 |
CA20052634479 |
申请日期 |
2005.12.23 |
申请人 |
UNIVERSITE DE GENEVE |
发明人 |
SCHUETZ, YANNIC;CARATTI-BESSON, VIRGINIE;JORDAN, OLIVIER;GURNY, ROBERT |
分类号 |
A61K9/00;A61K9/19;C08B37/00;C08L5/08 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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