| 摘要 |
<p>Substd. 2,3-dihydro- f -1,4-oxazepines of formula:- (where R1, R3, R4, R5, R6 (same or diff.) = H, lower (alkyl, alkenyl or alkinyl), substd. or unsubstd. aryl or aralkyl, aryloxy (or-thio) alkyl; R1 can also be pyridyl or pyrimidyl, directly alpha-linked or via C1-3 alkyl; R3 and R5 can form a C5-7 alkylated cyclic chain. A is an opt. substd. mono- or dicyclic arom. or hetero-ring), their acid addition and quat. ammon. salts and stereoisomers are muscle relaxants and spasmolytics. Preparation by treating with a cy clodehydrating agent e.g. POCl3, PCL3, PCl5, P2O5.</p> |
