NOVEL USE OF SUBSTITUTED AMINOMETHYL CHROMANS FOR THE TREATMENT OF MOVEMENT DISORDERS AND OF ADVERSE EFFECTS INDUCED BY DRUGS ADMINISTERED TO TREAT EXTRAPYRAMIDAL MOVEMENT DISORDERS

摘要

COMPOUNDS OF FORMULA I IN WHICH R1, R2, R3 AND N HAVE A MEANING AS INDICATED IN CLAIM 1, OR ONE OF THEIR OPTICAL ISOMERS OR PHARMACEUTICALLY ACCEPTABLE SALTS, USED FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF ADVERSE EFFECTS OF ANTI-PARKINSONIAN DRUGS IN EXTRAPYRAMIDAL MOVEMENT DISORDERS AND/OR FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF EXTRAPYRAMIDAL SYMPTOMS (EPS) INDUCED BY NEUROLEPTICS.A PREFERRED COMPOUND IS (-)-(R)-2 -{4-[[3,4-DIHYDRO-2H-BENZOPYRA N-2-YL)-METHYL] AMINO]BUTYL}-1,2-BENZOISOTHIAZOL-3-(2H)-ON-1, 1-DIOXIDE OR A PHYSIOLOGICALLY ACCEPTABLE SALT THEREOF.