| 发明名称 |
AEROSOL FORMULATIONS FOR PULMONARY ADMINISTRATION OF MEDICAMENTS TO PRODUCE A SYSTEMIC EFFECT |
| 摘要 |
The invention discloses an aerosol pharmaceutical composition comprising a medicament in solution in a mixture of a hydrofluoroalkane propellant and one or more co-solvents wherein the aerosol liquid droplets delivered on actuation of the inhaler have a particle size comprised between 0.5 microm and 2.5 microm, with a mass median aerodynamic diameter of about 1-2 microm and wherein the fine particle fraction is at least 30%. |
| 申请公布号 |
EA008571(B1) |
申请公布日期 |
2007.06.29 |
| 申请号 |
EA20040001006 |
申请日期 |
2003.02.26 |
| 申请人 |
CHIESI FARMACEUTICI S.P.A. |
发明人 |
DAVIES REBECCA, JAINE;GANDERTON DAVID;LEWIS DAVID, ANDREW;MEAKIN BRIAN, JOHN;BRAMBILLA GAETANO;FERRARIS ALESSANDRA |
| 分类号 |
A61K9/12;A61K9/00;A61K31/00;A61K31/4704;A61K31/485;A61K45/06;A61K47/10;A61K47/14;A61K47/34;A61P25/04 |
主分类号 |
A61K9/12 |
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