NON-NUCLEOSIDE REVERSE TRANCRIPTASE INHIBITORS

摘要

PROVIDED ARE COMPOUNDS OF THE GENERAL FORMULA I: WHEREIN R2 IS SELECTED FROM THE GROUP CONSISTING OF H, F, CL, (C1-4) ALKYL, (C3-4) CYCLOALKYL AND CF3 ; R4 IS H OR ME; R5 IS H, ME OR ET, WITH THE PROVISO THAT R4 AND R5 ARE NOT BOTH ME, AND IF R4 IS ME THEN R5 CANNOT BE ET; R11 IS ET, CYC1OPROPYL, PROPYL, ISOPROPYL, OR ISOBUTYL; AND Q IS SELECTED FROM THE GROUP CONSISTING OF: AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE, WILD-TYPE AND SEVERAL MUTANT STRAINS.