GSK-3 inhibiting compounds

摘要

Disclosed are compounds of formula (Ia) and (Ib) wherein: P represents a 5- or 6-membered heteroaromatic ring containing one or two heteroatoms selected independently from N, O and S of which at least one atom is N; R1 is H R2 and R3 are as defined in the specification; and m and n are independently 0, 1, 2, 3 or 4. The compounds disclosed are GSK3 inhibitors having good bioavailability useful in the treatment of disorders such as Alzheimer's Disease, chronic and acute neurodegenerative diseases, bipolar disorders, schizophrenia, diabetes and hair loss amongst others.