发明名称 |
RECOMBINANT HUMAN T2 RNASE AND USES THEREOF |
摘要 |
The cloning and heterologous expression of human T2 RNase6PL are disclosed. Further disclosed are methods for preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The methods are effected by administering to the subject a therapeutically effective amount of a RNase6PL ribonuclease or close homologues thereof. |
申请公布号 |
WO2006035439(A3) |
申请公布日期 |
2007.06.28 |
申请号 |
WO2005IL01041 |
申请日期 |
2005.09.28 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREWUNIVERSITY OF JERUSALEM;ROIZ, LEVAVA;SCHWARTZ, BETTY;SMIRNOFF, PATRICIA;SHOSEYOV, ODED |
发明人 |
ROIZ, LEVAVA;SCHWARTZ, BETTY;SMIRNOFF, PATRICIA;SHOSEYOV, ODED |
分类号 |
C12P21/06;A61K38/46;C07H21/04;C07K1/14;C07K1/16;C07K14/00;C12N1/20;C12N5/10;C12N9/16;C12N15/00;C12Q1/44 |
主分类号 |
C12P21/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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