发明名称 |
PHARMACEUTICAL COMPOSITION COMPRISING (E) -7- [4- (4-FLUOROPHENYL) -6-ISOPROPYL-2- [METHYL (METHYLSULFONYL) AMINO] PYRIMIDIN-5 -YL- (3R, 5S) -3, 5-DIHYDR0XYHEPT-6-EN0IC ACID |
摘要 |
A chemically stable formulation of (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R, 5S)-3,5-dihydroxyhept-6-enoic acid or a pharmaceutically-acceptable salt thereof for oral use, such as tablets, capsules, powders, granules has been developed using the substances which stabilize against formation of degradation products: lactone and oxidation product. |
申请公布号 |
CA2630704(A1) |
申请公布日期 |
2007.06.28 |
申请号 |
CA20062630704 |
申请日期 |
2006.12.18 |
申请人 |
LEK PHARMACEUTICALS D.D. |
发明人 |
JAKLIC, MIHA TOMAZ;NAVERSNIK, KLEMEN |
分类号 |
A61K31/505;A61P3/06;A61P9/10 |
主分类号 |
A61K31/505 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|