P2X4 RECEPTOR ANTAGONIST

摘要

A compound represented by the general formula (I) below or a salt thereof is used as a P2X<SUB>4</SUB> receptor antagonist. (I) (In the formula, X represents S or CH<SUB>2</SUB>; Y represents O, S or NH; R<SUP>1</SUP> represents a hydrogen atom, an alkyl group having 1-8 carbon atoms or the like; R<SUP>2</SUP> and R<SUP>3</SUP> respectively represent a hydrogen atom, an alkyl group having 1-8 carbon atoms, an alkoxy group having 1-8 carbon atoms, a halogen atom, a hydroxyl group or the like; R<SUP>4</SUP> and R<SUP>5</SUP> respectively represent a hydrogen atom, an alkyl group having 1-8 carbon atoms or the like; and a double line composed of a broken line and a solid line represents a single bond or a double bond.)