| 摘要 |
<p>An agent for the prevention and/or treatment of urine collection disorders associated with lower urinary tract obstructive disease, <Bold>characterized by</Bold> containing an indoline derivative represented by the following general formula (I):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="32" wi="92" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry>
wherein R represents optionally substituted aliphatic acyl optionally having an unsaturated bond, hydroxyalkyl, aliphatic acyloxyalkyl, lower alkoxy, carboxy, lower alkoxycarbonyl, aryl(lower alkoxy) carbonyl, carbamoyl, (mono- or,dialkyl)carbonyl or cyano(lower alkyl), optionally halogenated aromatic acyl, furoyl, or pyridylcarbonyl; R<Sup>1</Sup> represents cyano or carbamoyl; and R<Sup>2</Sup> represents lower alkyl optionally having a halogen atom, cyano group, or aryl group, or a pharmaceutically acceptable salt of the derivative. The derivative and salt are usable as an agent for the prevention and/or treatment of urine collection disorders associated with lower urinary tract obstructive disease.</p> |
