METHOD AND SYSTEM FOR DETERMINING THE CONCENTRATION OF AN ANALYTE/ENZYME COMPLEX OR OF AN ANALYTE/ENZYME CONJUGATE, ESPECIALLY FOR THE ELECTROCHEMICAL DETECTION OF THE ANALYTE, AND CORRESPONDING MEASURING DEVICE

摘要

The invention relates to a method for following the change in concentration of a redox-active substance, whereby suitable potentials for a reduction process or an oxidation process are applied to the working electrode of a measuring device. The invention is characterized in that the potential of the working electrode is pulsed and measuring phases and relaxation phases are alternately produced, the pulse lengths of measuring phase and relaxation phase being determined in a suitable manner. A rapid relaxation of the concentration gradient is electrochemically forced so that the measurement can be carried out on simple transducer arrays. A device for carrying out the method is characterized by comprising a transducer array (100, 200) in addition to a suitable potentiostat. The transducer array (100, 200) can consist of a planar metal substrate (1) on which at least one flexible insulator (2) is disposed, the metal surface and the insulator surface being firmly linked. The transducer array (200) can also comprise silicon-based CMOS structures.