VASCULAR EMBOLUS OF PACLITAXEL-SODIUM ALGINATE MICROSPHERE AND ITS PREPARATION

摘要

Vascular embolus of paclitaxel-sodium alginate microsphere and its preparation. The preparation of it consists of the following steps: preparing the solution of paclitaxel, sodium alginate and dilvalent metal cations such as BaCl 2 or CaCl 2 etc. by order; mixing the paclitaxel solution and sodium alginate solution, and then mixing them with the curing solution of BaCl 2 or CaCl 2 and the like. Then the obtained is the sodium alginate microshere vascular embolus containing paclitaxel. The carrier materials of the vascular embolus according to the invention are natural extracts and have good biocompatibility and re biodegradable; the side effect of the pharmaceutic loaded by them is minimal, and it is therefore suitable for the vascular embolism and chemotherapy against the tumor.