发明名称 USE OF BILE ACID OR BILE SALT FATTY ACID CONJUGATES
摘要 Use of a bile acid or bile salt fatty acid conjugate of general formula II W-X-G in which G is a bile acid or bile salt radical, which, if desired, is conjugated in position 24 with an amino acid, W stands for one or two fatty acid radicals having 14-22 carbon atoms and X stands for a suitable bonding member or for a direct C=C bond between said bile acid or bile salt radical and the fatty acid(s) or of a phannaceutical composition comprising same for the manufacture of a medicament for the reduction of the cholesterol in blood and for the treatment of hyperglycemia and diabetes, wherein said suitable bonding member provides a solid bond that is not substantially deconjugated during the absorption process of the conjugate.
申请公布号 EP1379254(B1) 申请公布日期 2007.06.20
申请号 EP20020761957 申请日期 2002.04.15
申请人 GALMED INTERNATIONAL LTD. 发明人 GILAT, TUVIA
分类号 A61K31/575;A61K47/48;A61P1/16;A61P3/06;A61P3/10;A61P7/00;A61P9/10;A61P43/00;C07J9/00;C07J41/00 主分类号 A61K31/575
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