发明名称 |
Adenovirus vectors, packaging cell lines, compositions, and methods for preparation and use |
摘要 |
The present invention relates to methods for gene therapy, especially to adenovirus-based gene therapy, and related cell lines and compositions. In particular, novel nucleic acid constructs and packaging cell lines are disclosed, for use in facilitating the development of high-capacity and targeted vectors. The invention also discloses a variety of high-capacity adenovirus vectors and related compositions and kits including the disclosed cell lines and vectors. Finally, the invention discloses methods of preparing and using the disclosed vectors, cell lines and kits.
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申请公布号 |
US7232899(B2) |
申请公布日期 |
2007.06.19 |
申请号 |
US20000482682 |
申请日期 |
2000.01.14 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
VON SEGGERN DANIEL J.;NEMEROW GLEN R. |
分类号 |
C07H21/04;A61K48/00;C07K14/075;C12N1/36;C12N15/00;C12N15/861;C12P21/06 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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