发明名称 |
Identification of Free-B-Ring Flavonoids as Potent COX-2 Inhibitors |
摘要 |
The present invention provides a novel method for inhibiting the cyclooxygenase enzyme COX-2. The method is comprised of administering a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids to a host in need thereof. The present also includes novel methods for the prevention and treatment of COX-2 mediated diseases and conditions. The method for preventing and treating COX-2 mediated diseases and conditions is comprised of administering to a host in need thereof an effective amount of a composition containing a Free-B-Ring flavonoid or a composition containing a mixture of Free-B-Ring flavonoids and a pharmaceutically acceptable carrier. |
申请公布号 |
US2007135359(A1) |
申请公布日期 |
2007.06.14 |
申请号 |
US20070676528 |
申请日期 |
2007.02.20 |
申请人 |
UNIGEN PHARMACEUTICALS, INC. |
发明人 |
JIA QI;NICHOLS TIMOTHY C.;RHODEN ERIC E.;WAITE SCOTT |
分类号 |
A61K31/7048;A61K31/353 |
主分类号 |
A61K31/7048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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