COMPOSITIONS AND METHODS FOR DECREASING MICRORNA EXPRESSION FOR THE TREATMENT OF NEOPLASIA
摘要
The invention generally features compositions and methods that are useful for treating or diagnosing a neoplasia. The invention is based in part on the observation that c-Myc activated expression of a cluster of six miRNAs on human chromosome 13. Accordingly, the invention provides therapeutic compositions and methods for altering the expression of a microRNA of the invention thereby treating a neoplasia, as well as compositions and methods for diagnosing a neoplasia.
申请公布号
WO2006133022(A3)
申请公布日期
2007.06.14
申请号
WO2006US21613
申请日期
2006.06.02
申请人
THE JOHNS HOPKINS UNIVERSITY;MENDELL, JOSHUA, T.;O'DONNELL, KATHRYN, A.;ZELLER, KAREN, I.;WENTZEL, ERIC, A.;DANG, CHI, V.
