| 摘要 |
<p>The present invention relates to the use of at least one transferrin, preferably lactoferrin, to prepare a medicament for preventing and/or treating with great effectiveness destructive inflammation affecting mucous membranes, optionally associated with states of hypoferremia and/or anemia and/or acute and chronic infections. The destructive inflammation is caused, for example, by pathological conditions during pregnancy and by infections sustained by intracellular or adhered or biofilm-protected pathogens. The invention has shown in fact a powerful antiinflammatory activity in returning state of pathological phlogosis to physiological and no longer destructive levels, accompanied by a concurrent regulatory activity on the passage of iron from tissues to circulation and on the development or dissemination of pathogens together with the inhibition of the forming of superoxides, which are also involved in cell damage and in destructive inflammation. The action of the transferrins described here is achieved by means of their topical and/or oral administration. If a particularly augmented effect on the states of anemia and hypoferremia is to be achieved, it is advantageous to combine the two types of oral and topical administration. A combined preparation for simultaneous, sequential or separate use is also described which comprises, as active components, a first composition for topical administration of at least one transferrin and a second composition for oral administration of at least one transferrin.</p> |
