| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing a biphenyl derivative, which is excellent in industrial productivity, by using inexpensive and readily available raw materials. SOLUTION: The method for the producing the biphenyl derivative represented by general formula (1) comprises reacting a chlorine atom of a benzene derivative represented by general formula (2) with metallic magnesium to form a Grignard reagent and coupling two molecules of the Grignard reagent with each other in the presence of a catalyst, with the proviso that in formulas (1) and (2), As are each at least one selected from trifluoromethyl group and fluorine; X is a halogen atom; n are each an integer of 1 to 4; a and b are each an integer and total of a and b is 1-8. COPYRIGHT: (C)2007,JPO&INPIT
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