发明名称 Preparation of monoclonal antibody to N-myc downstream regulated gene 2 and determination of NDRG2 using protein chip
摘要 The present invention relates to a monoclonal antibody specific for N-myc downstream regulated gene 2 (NDRG 2) protein, a cell line producing the monoclonal antibody, a method for measuring a quantity and quality of NDRG 2 protein, and a protein chip using the same. In the present invention, NDRG 2, a cancer-related factor is specifically expressed in dendritic cells differentiated from a monocyte of human peripheral blood. Accordingly, the monoclonal antibody specific for the NDRG 2 protein, the protein chip comprising the same and the method for measuring a quantity and quality of the NDRG 2 protein by using the same can be applied to elucidate characteristics of the dendritic cell and perform a research on the NDRG 2. Therefore, the present invention may help clinically to investigate and treat intractable diseases and cancers using the dendritic cell.
申请公布号 US2007128194(A1) 申请公布日期 2007.06.07
申请号 US20060393897 申请日期 2006.03.31
申请人 KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY 发明人 SONG EUN Y.;KIM JAE W.;LEE HEE G.;LIM JONG S.;CHOI SEUNG C.;CHO MI Y.;BAEK KYOUNG E.;KIM JIN S.;KIM JONG T.;YOON DO Y.;KWON DUR H.;PARK MI-YOUNG;YEOM YOUNG I.;CHOE YONG-KYUNG;KIM YOUNG-JUN
分类号 A61K39/395;C07K16/40;C12N5/06;G01N33/567 主分类号 A61K39/395
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