发明名称 |
IMMUNOGENIC COMPOSITIONS AGAINST HELICOBACTER INFECTION, POLYPEPTIDES FOR USE IN THE COMPOSITIONS AND NUCLEIC ACID SEQUENCES ENCODING SAID POLYPEPTIDES |
摘要 |
<p>There is provided an immunogenic composition capable of inducing protective antibodies against Helicobacter infection characterized in that it comprises:i) at least one sub-unit of a urease structural polypeptide from Helicobacter pylori, or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter felis urease, and/or at least one sub-unit of a urease structural polypeptide from Helicobacter felis, or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter pylori urease;ii) and/or, a heat shock protein (Hsp), or chaperonin, from Helicobacter, or a fragment of said protein.The preparation, by recombinant means, of such immunogenic compositions is also provided.</p> |
申请公布号 |
EP0703981(B1) |
申请公布日期 |
2007.06.06 |
申请号 |
EP19940917653 |
申请日期 |
1994.05.19 |
申请人 |
INSTITUT PASTEUR;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
LABIGNE, AGNES;SUERBAUM, SEBASTIEN;FERRERO, RICHARD;THIBERGE, JEAN-MICHEL |
分类号 |
C12N15/09;C12N15/31;A61K38/00;A61K39/00;A61K39/02;A61K39/106;A61K39/39;A61K39/395;A61P1/04;A61P3/02;A61P31/04;A61P35/00;A61P37/02;C07H21/04;C07K14/195;C07K14/205;C07K16/12;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/80;C12P21/02;C12P21/08;C12Q1/68;C12R1/19;G01N33/569;G01N33/574 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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