发明名称 |
Pure sodium salt of clavulanic acid |
摘要 |
The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]hept ane-2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.
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申请公布号 |
US4490295(A) |
申请公布日期 |
1984.12.25 |
申请号 |
US19800147584 |
申请日期 |
1980.05.07 |
申请人 |
BEECHAM GROUP P.1.C. |
发明人 |
FLEMING, IAN D.;NOBLE, DAVID;NOBLE (FORMERLY GILLETT), HAZEL M.;WALL, WILFRED F. |
分类号 |
C07D503/00;C12P17/18;(IPC1-7):C07D498/04;A61K31/42 |
主分类号 |
C07D503/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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