发明名称 Pharmaceutically-acceptable acid addition salts of certain methoxy- and ethoxy- amidine compounds, pharmaceutical formulations containing such salts and processes for obtaining them
摘要 Disclosed are pharmaceutically-acceptable sulfonic acid addition salts in at least a partially crystalline form of a compound of formula I wherein: R1 represents C1-2 alkyl substituted by one or more F substituents; R2 represents C1-2 alkyl; and n represents 0, 1 or 2. Salts of the type disclosed are useful for the treatment of diseases where inhibition of thrombin is required.
申请公布号 NZ536738(A) 申请公布日期 2007.05.31
申请号 NZ20030536738 申请日期 2003.05.27
申请人 ASTRAZENECA AB 发明人 AHLQVIST, MATTI;BOHLIN, MARTIN;INGHARDT, TORD;LUNDBLAD, ANITA;SIGFRIDSSON, CARL-GUSTAF
分类号 C07D205/04;A61K;A61K31/396;A61K31/397;A61P7/02;A61P9/04;A61P9/08;A61P9/10;A61P11/00;A61P25/28;A61P29/00;A61P31/04;A61P43/00;C07D;(IPC1-7):C07D205/04 主分类号 C07D205/04
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