发明名称 |
Pharmaceutically-acceptable acid addition salts of certain methoxy- and ethoxy- amidine compounds, pharmaceutical formulations containing such salts and processes for obtaining them |
摘要 |
Disclosed are pharmaceutically-acceptable sulfonic acid addition salts in at least a partially crystalline form of a compound of formula I wherein: R1 represents C1-2 alkyl substituted by one or more F substituents; R2 represents C1-2 alkyl; and n represents 0, 1 or 2. Salts of the type disclosed are useful for the treatment of diseases where inhibition of thrombin is required.
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申请公布号 |
NZ536738(A) |
申请公布日期 |
2007.05.31 |
申请号 |
NZ20030536738 |
申请日期 |
2003.05.27 |
申请人 |
ASTRAZENECA AB |
发明人 |
AHLQVIST, MATTI;BOHLIN, MARTIN;INGHARDT, TORD;LUNDBLAD, ANITA;SIGFRIDSSON, CARL-GUSTAF |
分类号 |
C07D205/04;A61K;A61K31/396;A61K31/397;A61P7/02;A61P9/04;A61P9/08;A61P9/10;A61P11/00;A61P25/28;A61P29/00;A61P31/04;A61P43/00;C07D;(IPC1-7):C07D205/04 |
主分类号 |
C07D205/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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