| 发明名称 |
MONOCLONAL ANTIBODIES AGAINST CLAUDIN-18 FOR TREATMENT OF CANCER |
| 摘要 |
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder. |
| 申请公布号 |
CA2628126(A1) |
申请公布日期 |
2007.05.31 |
| 申请号 |
CA20062628126 |
申请日期 |
2006.11.24 |
| 申请人 |
GANYMED PHARMACEUTICALS AG;JOHANNES GUTENBERG-UNIVERSITAET MAINZ, VERTRETEN DURCH DEN PRAESIDENTEN</SNM |
发明人 |
SCHROEDER, ANJA KRISTINA;FRITZ, STEFAN;GEPPERT, HARALD-GERHARD;UHEREK, CRISTOPH;TUERECI, OEZLEM;SAHIN, UGUR;THIEL, PHILIPPE;USENER, DIRK;BRANDENBURG, GUNDA |
| 分类号 |
C07K16/30;A61K39/395;A61K47/48;A61P35/00;C12N5/12 |
主分类号 |
C07K16/30 |
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