SUBSTITUTED THIOPHENES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENT COMPRISING THEM

摘要

SUBSTITUTED THIOPHENE, PROCESSES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENT COMPRISING THEMTHE INVENTION RELATES TO SUBSTITUTED THIOPHENE DERIVATIVES OF THE FORMULA 1, WHERE R1 TO R8 ARE AS DEFINED IN THE CLAIMS.MEDICAMENTS COMPRISING COMPOUNDS OF THIS TYPE ARE OF USE FOR PREVENTING OR TREATING VARIOUS DISORDERS. THUS, THE COMPOUNDS CAN BE USED, INTER ALIA, FOR THE TREATMENT OF RESPIRATORY DISORDERS AND SNORING, AND FOR IMPROVING THE RESPIRATORY DRIVE, FOR THE TREATMENT OF ACUTE AND CHRONIC DISORDERS, DISORDERS INDUCED BY ISCHEMIC AND/OR REPERFUSION EVENTS AND BY PROLIFERATIVE OR FIBROTIC EVENTS, FOR THE TREATMENT OR PROPHYLAXIS OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM AND LIPID METABOLISM, AND DIABETES, BLOOD COAGULATION AND INFECTION BY PARASITES.