发明名称 |
IMAGING AND THERAPEUTIC METHOD USING MONOCYTES |
摘要 |
The invention relates to a method of treating or diagnosing a disease state mediated by monocytes. The method utilizes a composition comprising a conjugate or complex of the general formula A<SUB>b</SUB>-X wherein the group A<SUB>b</SUB> comprises a ligand that binds to monocytes, and when the conjugate is being used for treatment of the disease state, the group X comprises an immunogen, a cytotoxin, or a compound capable of altering monocyte function, and when the conjugate is being used for diagnosing the disease state, the group X comprises an imaging agent. |
申请公布号 |
WO2007006041(A3) |
申请公布日期 |
2007.05.31 |
申请号 |
WO2006US26484 |
申请日期 |
2006.07.05 |
申请人 |
PURDUE RESEARCH FOUNDATION;LOW, PHILIP, STEWART;HILGENBRINK, ANDREW, RICHARD |
发明人 |
LOW, PHILIP, STEWART;HILGENBRINK, ANDREW, RICHARD |
分类号 |
A61P37/00;A61K33/24;A61K35/14;A61K38/00;A61K38/03;A61K38/08;A61K39/00;A61K39/395;A61K49/06;A61P29/00 |
主分类号 |
A61P37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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