发明名称 |
ANTIBODY COMPOSITION SPECIFICALLY BINDING TO CD10 |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide an anti-CD10 antibody composition useful as a medicine having increased effector function. <P>SOLUTION: The antibody composition is composed of an antibody molecule specifically binding to CD10 and having an N-glycoside-binding complex sugar chain in the Fc region, wherein the N-glycoside-binding complex sugar chain is a sugar chain free from fucose bonding to the N-acetylglucosamine at the reducing terminal of the sugar chain. The invention further provides a transformant to produce the antibody composition, a method for producing the antibody composition, and a medicine containing the antibody composition. <P>COPYRIGHT: (C)2007,JPO&INPIT |
申请公布号 |
JP2007129903(A) |
申请公布日期 |
2007.05.31 |
申请号 |
JP20030350160 |
申请日期 |
2003.10.08 |
申请人 |
KYOWA HAKKO KOGYO CO LTD |
发明人 |
ONUKI NAOKO;SATO MITSUO;YANAGISAWA TAKU;HIJIKATA MARIKO;OTA SATOSHI;NAKANO RYOSUKE;NIWA RINHEI;WAKITANI MASAKO |
分类号 |
C12N15/09;A61K39/395;A61P1/04;A61P1/16;A61P9/10;A61P11/00;A61P19/02;A61P19/04;A61P25/00;A61P29/00;A61P35/00;A61P35/02;C07K16/32;C12N5/10;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|