摘要 |
The invention provides inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula (I), wherein ring A, ring B, R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4</SUB>, R<SUB>5</SUB>, m and n are as defined herein. |
申请人 |
GENENTECH, INC.;CURIS, INC.;GOLDSMITH, RICHARD, A.;SUTHERLIN, DANIEL, P.;ROBARGE, KIRK, D.;OLIVERO, ALAN, G. |
发明人 |
GOLDSMITH, RICHARD, A.;SUTHERLIN, DANIEL, P.;ROBARGE, KIRK, D.;OLIVERO, ALAN, G. |