发明名称 BISAMIDE INHIBITORS OF HEDGEHOG SIGNALING
摘要 The invention provides inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula (I), wherein ring A, ring B, R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4</SUB>, R<SUB>5</SUB>, m and n are as defined herein.
申请公布号 WO2007059157(A1) 申请公布日期 2007.05.24
申请号 WO2006US44240 申请日期 2006.11.14
申请人 GENENTECH, INC.;CURIS, INC.;GOLDSMITH, RICHARD, A.;SUTHERLIN, DANIEL, P.;ROBARGE, KIRK, D.;OLIVERO, ALAN, G. 发明人 GOLDSMITH, RICHARD, A.;SUTHERLIN, DANIEL, P.;ROBARGE, KIRK, D.;OLIVERO, ALAN, G.
分类号 C07D213/82;A61K31/167;A61K31/4164;A61K31/4196;A61K31/44;A61K31/444;A61K31/4453;A61K31/4545;A61K31/496;A61K31/5375;C07D231/14;C07D239/28;C07D277/56;C07D401/12;C07D417/12 主分类号 C07D213/82
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