发明名称 Pyrimidine derivatives for treatment of hyperproliferative disorders
摘要 Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R<SUP>2</SUP>, G, G', and G'' represent substituent groups and R<SUP>2a </SUP>represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
申请公布号 US2007117817(A1) 申请公布日期 2007.05.24
申请号 US20040573227 申请日期 2004.10.08
申请人 BAYER PHARMACEUTICALS CORPORATION 发明人 DIXON JULIE A.;NAGARATHNAM DHANAPALAN;ZHANG LEI;WANG CHUNGUANG;YIN LIN;CHEN YUANWEI;CHEN JIANQING;BEAR BRIAN;BRANDS MICHAEL;HILLISCH ALEXANDER;BIERER DONALD;WANG MING;FU WENLANG;HENTEMANN MARTIN F.;BULLION ANN-MARIE
分类号 A61K31/513;A61K31/506;A61K31/5377;C07D239/48;C07D401/12;C07D401/14;C07D403/02;C07D403/12;C07D405/14;C07D409/14;C07D413/14;C07D453/02 主分类号 A61K31/513
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