| 发明名称 |
RHESUS MONKEY DICKKOPF-1, NUCLEOTIDES ENCODING SAME, AND USES THEREOF |
| 摘要 |
The present invention provides rhesus monkey dickkopf-1 (rhDkk-1) and nucleotide sequences encoding it. Also provided herein are recombinant vectors, and recombinant hosts comprising rhDkk-1-encoding nucleotide sequences. Isolated rhDkk-1 can be used to screen and identify novel osteoanabolic compounds that stimulate bone formation for the treatment of osteoporosis or other disorders characterized by insufficient bone mass. |
| 申请公布号 |
WO2005049640(A3) |
申请公布日期 |
2007.05.24 |
| 申请号 |
WO2004US38489 |
申请日期 |
2004.11.12 |
| 申请人 |
MERCK & CO., INC.;HARADA, SHUN-ICHI;KASPARCOVA, VIERA;GLANTSCHNIG, HELMUT |
发明人 |
HARADA, SHUN-ICHI;KASPARCOVA, VIERA;GLANTSCHNIG, HELMUT |
| 分类号 |
C12N15/12;C07H21/04;C07K;C07K14/47;G01N33/567 |
主分类号 |
C12N15/12 |
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