| 发明名称 |
Hydrolytic kinetic resolution of cyclic substrates |
| 摘要 |
The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisomerically- and/or regioisomerically-enriched product. The present invention also relates to hydrolytic kinetic resolutions of racemic and diastereomeric mixtures of epoxides.
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| 申请公布号 |
US7220870(B2) |
申请公布日期 |
2007.05.22 |
| 申请号 |
US20050029887 |
申请日期 |
2005.01.05 |
| 申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
JACOBSEN ERIC N.;TOKUNAGA MAKOTO;LARROW JAY F. |
| 分类号 |
C07D303/04;C07D327/02;C07B53/00;C07B57/00;C07B61/00;C07C29/10;C07C31/20;C07C31/28;C07C31/42;C07C33/035;C07C33/26;C07C41/03;C07C41/26;C07C43/03;C07C43/13;C07C43/23;C07C45/64;C07C49/24;C07C67/29;C07C69/30;C07C213/02;C07C247/14;C07C269/06;C07C271/16;C07D203/06;C07D205/00;C07D301/32;C07D303/00;C07D303/08;C07D303/22;C07D303/32;C07D303/36;C07D303/40;C07D303/48;C07D307/00;C07D317/08;C07D317/36;C07F5/00;C07F7/08;C07F7/18 |
主分类号 |
C07D303/04 |
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