发明名称 |
IMPROVED METHOD FOR MAKING AMINO ACID CLYCOSIDES AND GLYCOPEPTIDES |
摘要 |
<p>The invention relates to an improved method of preparing amino glycosides and glycopeptides. The method involves reacting an diarylketimine with an amino acid having a hydroxal side chain to produce an imino-bound intermediate compound. This intermediate is then reacted with an acetylated sugar residue under suitable conditions to yield amino glycoside. The synthetic amino glycoside may be incorporated into a peptide chain under conditions compatible with standard glycopeptide synthesis reactions.</p> |
申请公布号 |
WO2007055698(A1) |
申请公布日期 |
2007.05.18 |
申请号 |
WO2005US41122 |
申请日期 |
2005.11.10 |
申请人 |
THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA;POLT, ROBIN |
发明人 |
POLT, ROBIN |
分类号 |
C07K5/00;A61K31/185;C07K5/06 |
主分类号 |
C07K5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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