| 摘要 |
<p num="1"><br/><br/><br/>The invention relates to 2-(benzimidazol-1-yl)-acetamide bisaryl derivative <br/>having the general Formula (I) wherein n is 0 or 1; Ar1 represents a diradical <br/>derived from a 5- or 6-membered aromatic ring, optionally comprising 1-3 <br/>heteroatoms selected from N, O and S, said ring being optionally substituted <br/>with (C1-4)alkyl, (C1-4)alkyloxy, halogen, CF3 or cyano; Ar2 represents a 6-<br/>membered aryl ring, optionally comprising 1-3 nitrogen atoms, said ring being <br/>optionally substituted with 1-3 substituents selected from (C1-4)alkyl <br/>(optionally substituted with 1 or more halogens), (C1-4)alkyloxy (optionally <br/>substituted with 1 or more halogens), di(C1-4)alkylamino, halogen, CF3 or <br/>cyano; or a pharmaceutically acceptable salt thereof; to pharmaceutical <br/>compositions comprising the same and to the use of said 2-(benzimidazol-1-yl)-<br/>acetamide bisaryl derivatives in the treatment of TRPV1 mediated disorders.<br/>
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