| 摘要 |
<p>The present invention provides a process for producing 2-halobenzoic acids of the general formula (I), characterized by reacting a benzoic acid of formula (II) with a halogenating agent in the presence of Pd catalyst: <CHEM> (wherein A is -OH, -OM (M is alkali metal), -N(R<6>)R<7> (R<6> and R<7> are each H, C1-C6 alkyl, optionally substituted phenyl, or the like); R is H, C1-C6 alkyl, C1-C6 alkylcarbonyl, carboxyl, C1-C12 alkoxycarbonyl, optionally substituted phenylcarbonyl, or the like; n is 0 to 4; X is Cl, Br or I, or alternatively (R)n may be present on benzene-constituting carbon atoms adjacent to each other and form a C3-C4 alkylene- or C3-C4 alkenylene-fused ring).</p> |
