| 发明名称 |
BISPECIFIC RELEASING MOLECULES CAPABLE TO RECOGNISE THE LYMPHOCYTE ANTIGEN CD2 AND THE NEOPLASTIC ANTIGENS |
| 摘要 |
The present invention relates to novel and highly effective bispecific antibody fragments which recognize lymphocyte CD2 antigen and any variable tumor antigen. Moreover, the invention relates to two new monoclonal antibodies termed AICD2.M1 and AICD2.M2. A combination of these antibodies, whereby at least one of them is a bispecfic antibody fragment, can be used successfully in tumor therapy and diagnostics. |
| 申请公布号 |
PL176761(B1) |
申请公布日期 |
1999.07.30 |
| 申请号 |
PL19940304510 |
申请日期 |
1994.08.01 |
| 申请人 |
MERCK PATENT GMBH |
发明人 |
STRITTMATTER WOLFGANG;JAEGGLE CARLOTA-SILVIA;MEUER STEFAN;BURKHART SCHRAVEN;WILD MARTIN |
| 分类号 |
G01N33/53;A61K38/00;A61K39/395;A61P35/00;C07K1/113;C07K14/485;C07K14/52;C07K14/705;C07K16/00;C07K16/18;C07K16/28;C07K16/30;C07K16/46;C07K19/00;C12N15/00;C12N15/02;C12N15/09;C12N15/13;C12N15/28;C12P21/08;C12R1/91;G01N33/531;G01N33/574 |
主分类号 |
G01N33/53 |
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