发明名称 |
UNIVERSAL CARRIER FOR TARGETING MOLECULES TO GB3 RECEPTOR EXPRESSING CELLS |
摘要 |
<p>The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: STxB is the Shiga Toxin B subunit or a functional equivalent thereof, Z is an amino-acid devoided of sulfydryl group, n being 0, 1 or a polypeptide, Cys is the amino-acid Cysteine. p</p> |
申请公布号 |
EP1355928(B1) |
申请公布日期 |
2007.05.16 |
申请号 |
EP20020700240 |
申请日期 |
2002.02.01 |
申请人 |
INSTITUT CURIE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI) |
发明人 |
JOHANNES, LUDGER;TARTOUR, ERIC;GOUD, BRUNO;FRIDMAN, WOLF, HERVE |
分类号 |
C07K14/25;C12N15/00;A61K38/00;A61K38/16;A61K39/385;A61K47/48;A61K48/00;A61P35/00;A61P43/00;C07K1/16;C07K17/00;C07K19/00;C12N1/21;C12N15/31;C12P21/00;C12Q1/68 |
主分类号 |
C07K14/25 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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