USE OF FRUCTOSE-BASED COMPOUNDS FOR THE DIAGNOSIS OF CANCER
摘要
This invention relates to compositions, methods utilizing fructose and other monosaccharides for the diagnosis of cancer. Cancer cells have shown a higher level of fructose utilization as compared to glucose. Further, cancer cells have shown a preferential use of fructose for nucleic acid synthesis. The present invention takes advantage of these features and provides for fructose or fructose-based compositions for the diagnosis of cancer using imaging techniques such as positron emission tomography.
申请公布号
WO2007025282(A9)
申请公布日期
2007.05.10
申请号
WO2006US33643
申请日期
2006.08.24
申请人
CEDARS-SINAI MEDICAL CENTER;HEANEY, ANTHONY, P.;HUI, HONGXIANG;WAXMAN, ALAN