发明名称 |
Influenza vaccines including combinations of particulate adjuvants and immunopotentiators |
摘要 |
<p>Influenza vaccines containing insoluble particulate adjuvants have been found to elicit an IgG response that is primarily a TH2 response (IgG1). This response can be shifted towards a TH1 response (IgG2a) by including immunopotentiators in the compositions. Thus the invention provides an immunogenic composition comprising: (i) an influenza virus antigen; (ii) an insoluble particulate adjuvant; and (iii) a immunopotentiator.</p> |
申请公布号 |
AU2006310339(A1) |
申请公布日期 |
2007.05.10 |
申请号 |
AU20060310339 |
申请日期 |
2006.11.06 |
申请人 |
NOVARTIS VACCINES AND DIAGNOSTICS SRL |
发明人 |
RINO RAPPUOLI;DEREK O'HAGAN;GUISEPPE DEL GUIDICE |
分类号 |
A61K39/145;A61K39/39 |
主分类号 |
A61K39/145 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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