摘要 |
Stabilized forms of gpl20 polypeptide, nucleic acids encoding these stabilized forms, vectors comprising these nucleic acids, and methods of using these polypeptides, nucleic acids, vectors and host cells are disclosed. Crystal structures and computer systems including atomic coordinates for stabilized forms of gpl20, and gpl20 with an extended V3 loop, and methods of using these structures and computer systems are also disclosed. |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES;DANA FARBER CANCER INSTITUTE, INC.;KWONG, PETER;MASCOLA, JOHN;NABEL, GARY;WYATT, RICHARD;DEY, BARNA;XU, LING;ZHOU, TONGQING;HUANG, CHIH-CHIN;SODROSKI, JOSEPH;YUAN, WEN;XIANG, SHI-HUA |
发明人 |
KWONG, PETER;MASCOLA, JOHN;NABEL, GARY;WYATT, RICHARD;DEY, BARNA;XU, LING;ZHOU, TONGQING;HUANG, CHIH-CHIN;SODROSKI, JOSEPH;YUAN, WEN;XIANG, SHI-HUA |