摘要 |
Compounds of general structure (I), wherein the central benzene ring may be substituted in the meta- or para-position; -A is an optionally substituted hydroxyl, alkoxyl, hydroxylamine, alkoxylamine or amine radical; -W is an N- and C-linked biradical selected from several possibilities; and -Z is a carbon radical selected from several possibilities. These compounds are PPARgamma and PPARgamma/PPARdelta modulators and, therefore, are useful for the prophylactic and/or curative treatment of a condition or a disease mediated by these recetpcors. |
申请人 |
LABORATORIOS S.A.L.V.A.T., S.A. |
发明人 |
FERNANDEZ SERRAT, ANNA;SERRA COMAS, CARMEN;BALSA LOPEZ, DOLORS;LLEBARIA SOLDEVILA, AMADEU;FARRERONS, GALLEMI, CARLES;MIQUEL BONO, IGNACIO JOSE;CATENA RUIZ, JUAN LORENZO;LAGUNAS ARNAL, CARMEN;CORDOMY MONTOYA, ARNAU;SALCEDO ROCA, CAROLINA;TOLEDO MESA, NATIVIDAD;MARRERO GONZALEZ, PEDRO;HARO BAUTISTA, DIEGO;FERNANDEZ GARCYA, ANDRES |