PHOSPHORYLATED OR NON-PHOSPHORYLATED MPR AS DIAGNOSTIC MARKER OR THERAPEUTIC TARGET

摘要

The invention relates to the use of phosphorylated and/or non- phosphorylated membrane associated progesterone receptor component 1 (mPR or PGRMC 1 ) or progesterone membrane component 2 (PGRMC2), in particular of at least one isoform thereof, and to other proteins, in particular isoforms thereof, as diagnostic markers and/or therapeutic targets for diseases associated with aberrant biological phenotypes, reagents for influencing mPR and/or the abundance and/or activity of said other proteins and to the use of an appropriate assay.