TREATMENT OF DISEASES BY SUBCUTANEOUS ADMINISTRATION OF A VEGF ANTAGONIST

摘要

A method of reducing or preventing hypertension associated with administration of a vascular endothelial growth factor (VEGF) antagonist in a human subjects suffering from a disease or condition treatable with a VEGF antagonist in which is it desirable to reduce or prevent hypertension, wherein a VEGF antagonist is to be administered subcutaneously. The method is particularly useful for treatment of patients unresponsive to treatment with a VEGF inhibitor administered intravenously.