发明名称 |
IN VIVO GENERATION OF DNA, RNA, PEPTIDE, AND PROTEIN LIBRARIES |
摘要 |
<p>The present invention relates to a method for the in vivo generation of DNA, RNA, peptide and protein libraries by means of a genetic element harboring a viral or phage origin of replication that is independently reproduced by a viral or phage error-prone polymerase not physically linked to the genetic element within a host cell furthermore containing viral or phage auxiliary nucleotide sequences and proteins that are required for replication of the viral or phage genetic element. The nucleotide or nucleotides of interest to be diversified are introduced into the genetic element and physically linked to the viral or phage origin of replication.</p> |
申请公布号 |
WO2007039461(A1) |
申请公布日期 |
2007.04.12 |
申请号 |
WO2006EP66535 |
申请日期 |
2006.09.20 |
申请人 |
MEYER, ANDREAS;EICHHORN, ERIC |
发明人 |
MEYER, ANDREAS;EICHHORN, ERIC |
分类号 |
C12N15/10 |
主分类号 |
C12N15/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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