发明名称 |
USE OF A PARTIALLY NEUTRALIZED, ANIONIC (METH)ACRYLATE COPOLYMER AS A COATING FOR THE PRODUCTION OF A MEDICAMENT RELEASING ACTIVE SUBSTANCE AT REDUCED PH VALUES |
摘要 |
The invention relates to the use of a partially neutralized, anionic (meth)acrylate copolymer comprising radically polymerized units of 25 to 95 percent by weight of C<SUB>1</SUB> to C<SUB>4</SUB> alkyl esters of acrylic or methacrylic acid and 5 to 75 percent by weight of (meth)acrylate monomers with an anionic group, at least 4 percent of which are neutralized by means of a base, for producing a medicament that is provided with an active substance-containing core and is coated with the partially neutralized, anionic (meth)acrylate copolymer. Said medicament releases at least 30 percent of the active substance contained therein in 30 minutes at a pH at which the active substance is sufficiently soluble and stable and at which the corresponding medicament that is coated with the non-neutralized anionic (meth)acrylate polymer releases less than 10 percent of the active substance contained therein. |
申请公布号 |
WO2007006353(A3) |
申请公布日期 |
2007.04.12 |
申请号 |
WO2006EP03115 |
申请日期 |
2006.04.05 |
申请人 |
ROEHM GMBH;PETEREIT, HANS-ULRICH;ASSMUS, MANFRED |
发明人 |
PETEREIT, HANS-ULRICH;ASSMUS, MANFRED |
分类号 |
A61K9/50 |
主分类号 |
A61K9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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