METHOD OF DETECTING THE PRESENCE OR ACTIVITY OF G - PROTEIN COUPLED RECEPTOR 92 (GPR92)

摘要

We describe a method comprising detecting GPR92 modulated expression of an NF-?B, API, CRE or p53 sensitive reporter, preferably for detecting the presence, quantity, activity or a change in any of these of a GPCR. These methods are useful for identifying agonists and antagonists or inverse agonist of GPCRs. We also provide cells for use in these methods.