An improved method for selectively depleting hypoxic cells within the bone marrow is disclosed. The method can be used to enhance engraftment of hematopoietic stem cells (HSCs) in the bone marrow of a host subject. Also disclosed is a method for treating a cancer within the bone marrow of a host subject.
申请公布号
WO2007041546(A2)
申请公布日期
2007.04.12
申请号
WO2006US38553
申请日期
2006.09.29
申请人
GENETIX PHARMACEUTICALS, INC.;DANA-FARBER CANCER INSTITUTE, INC.;PAMAR, KALINDI;MAUCH, PETER;DOWN, JULIAN