| 摘要 |
A pharmaceutical composition comprising an interleukin-13 (IL-13) antibody, more particularly a monoclonal interleukin-13 antibody and one or more pharmaceutically acceptable excipients buffered to a pH of 4.5 - 6.0 with an acetate buffer. The composition may be used in treating IL-13 related disorders such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, COPD, scleroderma, inflammatory bowel disease and Hodgkin's lymphoma. Also claimed is a process for purifying an IL-13 antibody comprising one or more chromatographic steps selected from affinity chromatography and ion exchange chromatography. |
