发明名称 |
METHOD FOR TREATMENT OF RELAPSES IN ONCOGYNECOLOGICAL PATIENTS |
摘要 |
FIELD: medicine, oncology, gynecology. ^ SUBSTANCE: method involves trepanopuncture of flank bone wing, aspiration of bone marrow suspension in the amount 150-200 ml followed by incubation of suspension with chemopreparations cisplatin and cyclophosphan at temperature 37°C for 40 min in doses above therapeutic ones. Doxorubicin is not incubated with bone marrow suspension and chemopreparations are administrated separately by intravenous route, by drops in indicated order in day when the bone marrow suspension has been taken, and this procedure is repeated with interval for 3-4 weeks but totally 4 times per one treatment course. Proposed method provides attaining the stable anti-tumor effect up to the complete tumor regression in this category of patients showing high tolerance to chemotherapy, and in practical absence of adverse toxic responses. Invention can be used in treatment of patients with relapses of ovary and uterus body cancer in case absence effectiveness of other methods of treatment or in case of their low effectiveness. ^ EFFECT: improved method of treatment. ^ 2 ex |
申请公布号 |
RU2296564(C2) |
申请公布日期 |
2007.04.10 |
申请号 |
RU20050108771 |
申请日期 |
2005.03.28 |
申请人 |
ROSTOVSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ ONKOLOGICHESKIJ INSTITUT MZ RF;SIDORENKO JURIJ SERGEEVICH;NERODO GALINA ANDREEVNA;GOLOTINA LJUDMILA JUR'EVNA;GOROSHINSKAJA IRINA ALEKSANDROVNA;ZLATNIK ELENA JUR'EVNA;BIRJUKOVA ANNA ALEKSANDROVNA |
发明人 |
SIDORENKO JURIJ SERGEEVICH;NERODO GALINA ANDREEVNA;GOLOTINA LJUDMILA JUR'EVNA;GOROSHINSKAJA IRINA ALEKSANDROVNA;ZLATNIK ELENA JUR'EVNA;BIRJUKOVA ANNA ALEKSANDROVNA |
分类号 |
A61K31/282;A61K31/675;A61K31/704;A61M1/36;A61P35/00 |
主分类号 |
A61K31/282 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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